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Neuroscience
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March 18, 2026 · 8 min read

The Default Mode Network: How Psilocybin Rewires Thought Patterns

There's a part of your brain that never shuts up. It's running when you're lying in bed at 3am replaying a conversation from six years ago. It's the narrator, the voice that stitches together your memories, your anxieties, and your sense of who you are. Neuroscientists call it the Default Mode Network. And psilocybin, it turns out, is one of the few things that can make it quiet.

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